Description

Ac-Cys-Glu-His-D-Phe-Arg-Trp-Cys-Lys-Pro-Val-Nh2 is a synthetic peptide derivative, specifically a modified analog of α-Melanocyte-Stimulating Hormone (α-MSH). This compound matters for its role in advanced research and development within the life sciences, offering a precise tool for studying melanocortin receptor interactions and signaling pathways. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on endocrinology, dermatology, and metabolic disorder research.

Application

• Biomedical Research: As a key reference standard and tool compound for studying the structure-activity relationship (SAR) of melanocortin peptides and their receptors (MC1R, MC3R, MC4R, MC5R).
• Drug Discovery: Serving as a lead compound or intermediate in the development of novel therapeutics targeting pigmentation disorders, inflammation, and energy homeostasis.
• Biochemical Assays: Utilized in competitive binding assays, receptor activation studies, and signal transduction pathway analysis to evaluate potency and efficacy of new candidates.
• Academic Studies: Fundamental research into peptide chemistry, hormone action, and the physiological roles of melanocortin systems in various biological processes.
• Peptide Library Synthesis: Acts as a specialized building block or template for creating focused libraries of peptide analogs for high-throughput screening.

Basic Information

Product Name	Ac-Cys-Glu-His-D-Phe-Arg-Trp-Cys-Lys-Pro-Val-Nh2
CAS No.	91050-39-4
Molecular Formula	C73H105N23O18S2
Molecular Weight	1640.9 g/mol
Synonyms	Ac-[Cys4,10, D-Phe7]-α-MSH(4-13)-NH2; Ac-[Cys4, D-Phe7, Cys10]-α-MSH(4-13)-NH2; Cyclo(4-10)[Cys4, D-Phe7, Cys10]-Ac-α-MSH(4-13)-NH2; Melanotan II analog; MT-II analog; SHU 9119; Ac-cyclo[Cys4, D-Phe7, Cys10]-α-MSH(4-13)-NH2; Ac-Nle-cyclo[Asp5, D-Phe7, Lys10]-α-MSH(4-10)-NH2 analog
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems. Each batch of Ac-Cys-Glu-His-D-Phe-Arg-Trp-Cys-Lys-Pro-Val-Nh2 undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing batch-specific results. Our quality commitment aligns with standards suitable for research and development applications, ensuring reliable and reproducible performance in your experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Peptide Content)	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC/IC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.