Description

Glycyl-Arginyl-Glycyl-Aspartyl-Seryl-Proline is a synthetic hexapeptide sequence with the CAS number 91037-75-1. This compound is of significant interest for its role in mimicking cell adhesion motifs, particularly the Arg-Gly-Asp (RGD) sequence, which is critical for integrin binding. It is primarily utilized by researchers and manufacturers in the life sciences and pharmaceutical development sectors. This peptide serves as a key biochemical tool for studying cellular interactions and developing targeted therapeutic agents.

Application

• Biomedical Research: Used as a standard or inhibitor in studies of cell adhesion, migration, and integrin-mediated signaling pathways.
• Drug Discovery: Serves as a lead compound or scaffold for developing novel therapeutics targeting cardiovascular diseases, cancer metastasis, and bone disorders.
• Biomaterial Coating: Functionalizes surfaces of medical implants, scaffolds, and diagnostic devices to enhance biocompatibility and cellular integration.
• Diagnostic Assay Development: Employed in the development of ELISA kits and other bioassays to detect specific integrin interactions or antibodies.
• Pharmaceutical Intermediates: Acts as a critical building block in the synthesis of more complex peptide-based pharmaceuticals.
• Cosmeceutical Formulations: Investigated for potential use in advanced skincare products aimed at promoting skin repair and regeneration.

Basic Information

Product Name	Glycyl-Arginyl-Glycyl-Aspartyl-Seryl-Proline
CAS No.	91037-75-1
Molecular Formula	C25H42N12O10
Molecular Weight	646.68 g/mol
Synonyms	GRGDSP Peptide; Gly-Arg-Gly-Asp-Ser-Pro; GRGDSP Hexapeptide; Arg-Gly-Asp (RGD) Containing Peptide; H-Gly-Arg-Gly-Asp-Ser-Pro-OH; Adhesion Peptide GRGDSP; Cell Adhesion Peptide; Fibronectin Fragment Peptide
EINECS	Contact for details

Quality Control

Our Glycyl-Arginyl-Glycyl-Aspartyl-Seryl-Proline is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each lot undergoes comprehensive analytical testing including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere or desiccant after each use to prevent degradation. For short-term use, store at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	Within ± 10% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.