Description

H-Gly-Arg-Gly-Asp-Ser-Cys-Oh is a synthetic peptide sequence, also known as GRGDSC, representing a key fragment of the fibronectin cell-binding domain. This compound matters as a critical research tool for studying cell adhesion, migration, and signaling pathways mediated by integrin receptors. It is primarily needed by researchers and manufacturers in the fields of biomedical research, tissue engineering, and pharmaceutical development for applications ranging from surface coating to drug discovery.

Application

• Biomedical Research: Used as a substrate to study integrin-mediated cell adhesion, spreading, and signaling in vitro.
• Tissue Engineering: Coated onto biomaterial surfaces (e.g., polymers, hydrogels) to promote specific cellular attachment and growth.
• Drug Discovery: Serves as a reference standard or competitive inhibitor in assays screening for anti-adhesion or anti-angiogenesis compounds.
• Diagnostic Development: Employed in the functionalization of biosensors or assay plates to capture specific cell types.
• Bioconjugation: The cysteine (Cys) residue provides a thiol group for site-specific conjugation to carrier proteins, surfaces, or other molecules.
• Neuroscience Studies: Applied in research on neuronal cell guidance, axon growth, and neural network formation on patterned surfaces.

Basic Information

Product Name	H-Gly-Arg-Gly-Asp-Ser-Cys-Oh
CAS No.	91037-71-7
Molecular Formula	C20H34N10O9S
Molecular Weight	590.62 g/mol
Synonyms	GRGDSC Peptide; Gly-Arg-Gly-Asp-Ser-Cys; Fibronectin Cell-Adhesion Peptide Fragment; H-Gly-Arg-Gly-Asp-Ser-Cys-OH; Arg-Gly-Asp-Ser-Cys Peptide; Adhesion Peptide GRGDSC; CAS 91037-71-7
EINECS	Contact for details

Quality Control

Our H-Gly-Arg-Gly-Asp-Ser-Cys-Oh is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 70%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.