Description

Arg-Gly-Asp-Ser (RGDS) is a synthetic tetrapeptide sequence that mimics a key cell adhesion motif found in extracellular matrix proteins like fibronectin. This compound is crucial for research and development in biomaterials and targeted therapeutics due to its specific inhibitory activity against integrin receptors. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biomedical engineering, and life science research sectors for applications ranging from drug discovery to surface functionalization.

Application

• Biomaterial Surface Modification: Coating medical devices, implants, and tissue engineering scaffolds to promote specific cell adhesion and integration.
• Cell Biology Research: Used as a competitive inhibitor in studies of integrin-mediated cell adhesion, migration, and signaling pathways.
• Drug Discovery & Development: Serving as a lead compound or targeting moiety in the design of novel anti-thrombotic, anti-angiogenic, and anti-cancer therapeutics.
• Diagnostic Assay Development: Functionalizing surfaces for cell-based assays or biosensors to study receptor-ligand interactions.
• Peptide Synthesis & Custom Manufacturing: Used as a building block or reference standard for the synthesis of larger, more complex bioactive peptides.

Basic Information

Product Name	Arg-Gly-Asp-Ser
CAS No.	91037-65-9
Molecular Formula	C17H30N8O8
Molecular Weight	474.47 g/mol
Synonyms	RGDS Peptide; Arg-Gly-Asp-Ser Tetrapeptide; RGD Peptide; RGD Sequence; Adhesion Peptide; Fibronectin Cell Adhesion Peptide; L-Arginylglycyl-L-α-aspartyl-L-serine; H-Arg-Gly-Asp-Ser-OH
EINECS	Contact for details

Quality Control

Our Arg-Gly-Asp-Ser is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) detailing specifications such as purity (by HPLC), amino acid composition, and peptide content. Our quality commitment supports applications requiring research-grade to GMP-grade materials, with documentation available to meet rigorous regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and storage under inert atmosphere. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥95%
Peptide Content	≥80%
Amino Acid Composition	Conforms to theoretical ratio
Water Content (KF)	≤5.0%
Acetate Content (HPIC)	≤10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.