Description

Fmoc-L-Arginine CAS NO 91000-69-0 is a protected derivative of the essential amino acid L-arginine, featuring a fluorenylmethyloxycarbonyl (Fmoc) group on the α-amino function. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled and sequential assembly of complex peptides and proteins. It is indispensable for researchers and manufacturers in pharmaceutical development, biotechnology, and proteomics who require high-purity, sequence-specific peptide intermediates.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid for the automated, stepwise construction of peptides.
• Pharmaceutical Research & Development: For synthesizing peptide-based drug candidates, hormones, and therapeutic agents.
• Bioconjugation & Protein Engineering: Used to introduce arginine residues into synthetic peptides for labeling, cross-linking, or modifying biological activity.
• Combinatorial Chemistry Libraries: Serves as a fundamental component for creating diverse peptide libraries for high-throughput screening.
• Diagnostic Reagent Production: Employed in the manufacture of synthetic peptide antigens for immunoassays and diagnostic kits.
• Academic & Industrial Research: A standard reagent in biochemistry and molecular biology laboratories for studying protein structure and function.

Basic Information

Product Name	Fmoc-L-Arginine
CAS No.	91000-69-0
Molecular Formula	C21H24N4O4
Molecular Weight	396.44 g/mol
Synonyms	Fmoc-Arg-OH; N-α-Fmoc-L-arginine; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-guanidinopentanoic acid; Fmoc-L-Arg; Fmoc-Arginine; N-Fmoc-L-arginine; Fmoc-Arg; Fmoc-L-Arginine-OH
EINECS	Contact for details

Quality Control

Our Fmoc-L-Arginine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation by IR and NMR spectroscopy. We provide comprehensive Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with research and cGMP-grade standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Specific Rotation	+10.0° to +12.0° (c=1 in DMF)
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.