Description

Atrial Natriuretic Factor (3-28) (Rat) is a specific bioactive peptide fragment derived from the rat atrial natriuretic peptide (ANP) precursor. This compound is a critical research tool for studying the structure-activity relationships, receptor binding, and physiological effects of natriuretic peptides in cardiovascular and renal research. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and contract research organizations (CROs) focused on hypertension, heart failure, and renal function.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating the natriuretic peptide system, including receptor-ligand interactions and signal transduction pathways.
• Pharmacological Assays: Serves as a key reagent in in vitro and in vivo bioassays to evaluate vasodilation, diuresis, and natriuresis for drug discovery programs.
• Antibody Production & Immunoassays: Acts as an antigen for the generation of specific antibodies used in ELISA, RIA, and immunohistochemistry applications.
• Metabolic Studies: Employed in research to understand the metabolism, clearance, and degradation pathways of ANP fragments.
• Academic & Institutional Research: Fundamental tool for university laboratories and research institutes exploring cardiovascular physiology and endocrinology.

Basic Information

Product Name	Atrial Natriuretic Factor (3-28) (Rat)
CAS No.	90984-99-9
Molecular Formula	C124H202N40O39S2
Molecular Weight	2821.3 g/mol
Synonyms	ANF (3-28), rat; Atriopeptin (3-28); ANP (3-28), rat; Atrial Natriuretic Peptide (3-28) fragment, rat; Cardionatrin (3-28); rANP (3-28); H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH (Disulfide bridge: Cys7-Cys23)
EINECS	Contact for details

Quality Control

Our Atrial Natriuretic Factor (3-28) (Rat) is produced and controlled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all test results to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.