Description

Nerve Growth Factor (75-88) CAS NO 90983-17-8 is a synthetic peptide fragment corresponding to the beta subunit of the native Nerve Growth Factor (NGF) protein. This specific sequence is critical for research into neurotrophic signaling, neuronal development, and survival mechanisms. It is an essential biochemical tool for neuroscientists, pharmaceutical researchers, and biotechnology companies focused on neurodegenerative diseases, neuropathic pain, and neuroregeneration.

Application

• Neuroscience Research: Used as a key reagent in studies of neuronal differentiation, axon guidance, and cell survival pathways in vitro and in vivo.
• Drug Discovery & Development: Serves as a reference standard and active agent in high-throughput screening assays for novel neuroprotective or neuro-regenerative therapeutics.
• Biochemical Assays: Employed in ELISA development, receptor binding studies, and functional activity tests to quantify NGF or its receptor interactions.
• Cell Culture Supplement: Added to media to promote the survival and maintenance of primary neuronal cultures, such as sympathetic and sensory neurons.
• Academic & Institutional Research: Fundamental tool for investigating the role of NGF in development, plasticity, and disease models like Alzheimer's and Parkinson's.
• Diagnostic Development: Potential use in calibrating diagnostic kits aimed at measuring NGF levels in biological samples for clinical research.

Basic Information

Product Name	Nerve Growth Factor (75-88)
CAS No.	90983-17-8
Molecular Formula	C70H113N21O22S
Molecular Weight	1560.8 g/mol
Synonyms	NGF (75-88); β-NGF (75-88); Nerve Growth Factor Beta Chain (75-88); NGF-β (75-88); NGF Peptide Fragment (75-88); H-Ser-His-Pro-Val-Phe-His-Asn-Gly-Ser-Val-Cys-Val-Leu-Ser-OH; NGF Active Site Peptide; Neurotrophin Peptide Fragment
EINECS	Contact for details

Quality Control

Our Nerve Growth Factor (75-88) is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep under inert atmosphere. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Amino Acid Composition	Conforms to theoretical values
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.