Description

4-Amino-2-(1-piperidinyl)pyrimidine-5-carbonitrile is a high-purity, heterocyclic organic compound featuring a pyrimidine core substituted with amino, piperidinyl, and nitrile functional groups. This unique structure makes it a versatile and critical building block in advanced organic synthesis, particularly for the development of novel pharmacologically active molecules. It is primarily sought after by pharmaceutical R&D and fine chemical manufacturers engaged in creating new drug candidates and specialized agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products.
• Chemical Synthesis: Serves as a versatile scaffold for constructing complex heterocyclic libraries in medicinal chemistry.
• Material Science: Potential building block for organic electronic materials and specialty polymers.
• Academic & Contract Research: Essential for research in organic chemistry and drug discovery programs at universities and CROs.

Basic Information

Product Name	4-Amino-2-(1-piperidinyl)pyrimidine-5-carbonitrile
CAS No.	90973-23-2
Molecular Formula	C10H13N5
Molecular Weight	203.25 g/mol
Synonyms	4-Amino-2-piperidin-1-ylpyrimidine-5-carbonitrile; 2-(1-Piperidinyl)-4-amino-5-cyanopyrimidine; 4-Amino-2-(piperidin-1-yl)pyrimidine-5-carbonitrile; 5-Cyano-2-piperidino-4-aminopyrimidine; 90973-23-2; 4-Amino-2-piperidin-1-yl-pyrimidine-5-carbonitrile; 2-Piperidin-1-yl-4-amino-pyrimidine-5-carbonitrile
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity. Our products undergo rigorous testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We can support development and commercial projects requiring compliance with cGMP, ICH Q7, and other relevant regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.