Description

3-Bromo-4-Chloro-1H-Pyrazolo[3,4-D]Pyrimidine is a high-value, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents, particularly kinase inhibitors targeting various therapeutic areas. It is primarily sought after by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the creation of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule kinase inhibitors for oncology and inflammatory diseases.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Chemical Biology: Serves as a versatile scaffold for constructing molecular probes and tool compounds to study biological pathways.
• Material Science: Potential building block for creating novel organic electronic materials or metal-organic frameworks (MOFs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Item	Detail
Product Name	3-Bromo-4-Chloro-1H-Pyrazolo[3,4-D]Pyrimidine
CAS No.	90914-41-3
Molecular Formula	C5H2BrClN4
Molecular Weight	233.45 g/mol
Synonyms	3-Bromo-4-chloro-1H-pyrazolo[3,4-d]pyrimidine; 4-Chloro-3-bromo-1H-pyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidine, 3-bromo-4-chloro-; 3-Bromo-4-chloro-7H-pyrazolo[3,4-d]pyrimidine; 3-Bromo-4-chloro-1H-pyrazolo[3,4-d]pyrimidine (ACI); 90914-41-3 (CAS RN)
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-4-Chloro-1H-Pyrazolo[3,4-D]Pyrimidine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting your regulatory and research requirements. A Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.