Description

Atriopeptin Iii (Rat) is a specific peptide fragment derived from rat atrial natriuretic peptide (ANP), a key hormone in cardiovascular and renal physiology. This high-purity reference standard is critical for ensuring the accuracy and reproducibility of research data in life science applications. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and diagnostic developers working on cardiovascular disease models, natriuretic peptide signaling pathways, and bioanalytical method development.

Application

• Biomedical Research Standard: Serves as a critical reference material in quantitative assays for rat ANP and its metabolites.
• Cardiovascular Pharmacology: Used in studies investigating blood pressure regulation, natriuresis, and diuresis mechanisms in rodent models.
• Assay Development & Validation: Essential for calibrating and validating immunoassays (ELISA, RIA) and chromatographic methods (HPLC, LC-MS).
• Receptor Binding Studies: Employed in competitive binding assays to study the affinity and function of natriuretic peptide receptors (NPRs).
• Academic & Institutional Research: Supports fundamental research in endocrinology, renal physiology, and molecular biology.
• Quality Control in Diagnostics: Acts as a control standard in the manufacturing and QC of diagnostic kits targeting natriuretic peptides.

Basic Information

Product Name	Atriopeptin Iii (Rat)
CAS No.	90817-13-3
Molecular Formula	C106H165N35O34S3
Molecular Weight	~2480.8 g/mol
Synonyms	Atriopeptin III; Rat Atrial Natriuretic Peptide (7-23); ANP (7-23); Atrial Natriuretic Factor (7-23); Cardionatrin I (7-23); rANP (7-23); H-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH (Disulfide bridge: Cys7-Cys23)
EINECS	Contact for details

Quality Control

Our Atriopeptin Iii (Rat) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Solubility	Soluble in water or aqueous acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.