Description

Divaplon is a non-benzodiazepine anxiolytic agent belonging to the pyrazolopyrimidine class of compounds. Its primary value lies in its high selectivity and affinity for specific GABAA receptor subtypes, making it a compound of significant interest for advanced pharmaceutical research and development. This product is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on central nervous system (CNS) therapeutics.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control and analytical method development in drug manufacturing.
• Pharmacological Research: Critical for in vitro and in vivo studies investigating GABAA receptor pharmacology, mechanism of action, and structure-activity relationships (SAR).
• Drug Discovery & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) precursor in the synthesis of novel anxiolytic and sedative-hypnotic candidates.
• Metabolite Studies: Employed in the identification and quantification of metabolites during preclinical and clinical pharmacokinetic studies.
• Analytical Method Validation: Utilized to validate HPLC, LC-MS, and other chromatographic assays for purity and potency testing.

Basic Information

Item	Detail
Product Name	Divaplon
CAS No.	90808-12-1
Molecular Formula	C17H17N5O2
Molecular Weight	323.35 g/mol
Synonyms	4,5-Dihydro-7-methoxy-5-methyl-6-(3-methylphenyl)pyrazolo[4,3-c]pyridin-3(2H)-one; DW-A-29; CGS 20625; 7-Methoxy-5-methyl-6-(3-methylphenyl)-4,5-dihydro-2H-pyrazolo[4,3-c]pyridin-3-one; 6-(m-Tolyl)-7-methoxy-5-methyl-4,5-dihydro-2H-pyrazolo[4,3-c]pyridin-3-one
EINECS	Contact for details

Quality Control

Our Divaplon is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by IR and NMR, purity assessment by HPLC, and residual solvent analysis by GC, to ensure it meets the stringent requirements for pharmaceutical research. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.