Description

1H-Indole, 2,3-Dihydro-1-(Trifluoroacetyl)- (9Ci) is a specialized indole derivative, a key fluorinated building block in advanced organic synthesis. Its core value lies in enabling the precise introduction of the trifluoroacetyl group into complex molecular frameworks, a critical step for modulating the biological activity and physicochemical properties of target compounds. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoroacetyl group can enhance metabolic stability and bioactivity.
• Material Science Research: Serves as a precursor for developing specialty polymers and advanced organic electronic materials with unique fluorinated properties.
• Chemical Biology & Proteomics: Acts as a reactive handle or a tag in the design of chemical probes for studying enzyme function and protein interactions.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and for custom synthesis projects in contract research organizations (CROs).

Basic Information

Product Name	1H-Indole, 2,3-Dihydro-1-(Trifluoroacetyl)- (9Ci)
CAS No.	90732-28-8
Molecular Formula	C11H8F3NO
Molecular Weight	227.18 g/mol
Synonyms	1-(Trifluoroacetyl)indoline; 2,3-Dihydro-1-(trifluoroacetyl)-1H-indole; N-Trifluoroacetylindoline; Indoline, 1-(trifluoroacetyl)-; 1H-Indole-1-carboxylic acid, 2,3-dihydro-, trifluoroacetyl derivative; 90732-28-8; N-(Trifluoroacetyl)indoline
EINECS	Contact for details

Quality Control

Every batch of 1H-Indole, 2,3-Dihydro-1-(Trifluoroacetyl)- (9Ci) is manufactured and tested under a strict quality management system to ensure consistency and reliability for your critical synthesis work. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and your specific project requirements. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available upon request and with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.