Description

4,6-Dichloro-2-(Methylthio)-7H-Pyrrolo[2,3-D]Pyrimidine is a high-purity heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in serving as a versatile and critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anticancer agents, and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging its heterocyclic core for biological activity.
• Chemical Biology & Proteomics: Serves as a scaffold for designing chemical probes and molecular tools to study enzyme function and cellular processes.
• Material Science: Potential building block for organic electronic materials, such as semiconductors or light-emitting components, due to its electron-deficient pyrrolopyrimidine structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring high-fidelity halogenated heterocycles.

Basic Information

Product Name	4,6-Dichloro-2-(Methylthio)-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	90662-12-7
Molecular Formula	C7H5Cl2N3S
Molecular Weight	234.10 g/mol
Synonyms	4,6-Dichloro-2-methylsulfanyl-7H-pyrrolo[2,3-d]pyrimidine; 2-(Methylthio)-4,6-dichloro-7H-pyrrolo[2,3-d]pyrimidine; 4,6-Dichloro-2-(methylmercapto)-7H-pyrrolo[2,3-d]pyrimidine; Pyrrolo[2,3-d]pyrimidine, 4,6-dichloro-2-(methylthio)-7H-; 90662-12-7; 4,6-Dichloro-2-methylthio-7H-pyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-2-(Methylthio)-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.