Description

Somatotropin Releasing Hormone (1-37)Amide is a synthetic peptide analog of the endogenous growth hormone-releasing hormone (GHRH). This compound is of significant interest for its role in stimulating the synthesis and secretion of somatotropin (growth hormone) from the anterior pituitary gland. It is primarily utilized in advanced pharmaceutical research, clinical diagnostics, and the development of therapeutic agents for endocrine disorders.

Application

• Pharmaceutical Research & Development: As a critical reference standard and active pharmaceutical ingredient (API) in the development of novel growth hormone secretagogues and diagnostic tools.
• Endocrinology Studies: Used in in vitro and in vivo research to investigate the hypothalamic-pituitary axis, growth hormone regulation, and related metabolic pathways.
• Biochemical Assays: Serves as a key reagent in cell-based assays and receptor binding studies to evaluate the potency and efficacy of GHRH analogs.
• Therapeutic Agent Development: A potential candidate for the development of treatments for growth hormone deficiency, aging-related conditions, and metabolic syndromes.
• Diagnostic Manufacturing: Used in the production of diagnostic kits and calibrators for measuring growth hormone levels in clinical settings.

Basic Information

Product Name	Somatotropin Releasing Hormone (1-37)Amide
CAS No.	90599-36-3
Molecular Formula	C185H295N55O57S
Molecular Weight	4239.8 g/mol
Synonyms	GHRH (1-37) Amide; Growth Hormone-Releasing Hormone (1-37)NH2; Somatoliberin (1-37)amide; hpGRF (1-37)-OH; GRF (1-37); Human Pancreatic Growth Hormone-Releasing Factor (1-37); Growth Hormone Releasing Factor Amide; Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2
EINECS	Contact for details

Quality Control

Our Somatotropin Releasing Hormone (1-37)Amide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and stringent tests for related substances and residual solvents. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate at -20°C. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%
Peptide Content (UV)	≥ 80.0%
Water Content (KF)	≤ 8.0%
Acetate Content (IC)	≤ 15.0%
Biological Activity	Assessed by cell-based assay (COA)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.