Description

5-(Aminomethyl)Pyrimidine-2,4(1H,3H)-Dione Hydrochloride is a high-purity, pharmaceutically relevant chemical building block offered as a hydrochloride salt for enhanced stability and handling. This compound is a key synthetic intermediate in the development of nucleoside analogs and other active pharmaceutical ingredients (APIs). It is essential for research and production in the pharmaceutical, biotechnology, and fine chemical industries, where precise molecular construction is critical.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used in the study of enzyme inhibitors and as a precursor for modified nucleobases in probe development.
• Fine Chemical Synthesis: Serves as a specialized intermediate in multi-step organic syntheses for complex molecules.
• API Development: Employed in the research and scale-up phases of new active pharmaceutical ingredient manufacturing.
• Academic Research: A valuable reagent for universities and research institutions exploring nucleic acid chemistry and medicinal chemistry.

Basic Information

Product Name	5-(Aminomethyl)Pyrimidine-2,4(1H,3H)-Dione Hydrochloride
CAS No.	90585-93-6
Molecular Formula	C5H8N3O2 • HCl
Molecular Weight	193.60 g/mol
Synonyms	5-(Aminomethyl)uracil hydrochloride; 5-(Aminomethyl)-2,4(1H,3H)-pyrimidinedione hydrochloride; 5-(Aminomethyl)dihydro-2,4(1H,3H)-pyrimidinedione hydrochloride; 5-Carbamoylmethyluracil hydrochloride (common misnomer); 5-(Aminomethyl)-2,4-dihydroxypyrimidine hydrochloride; AMU hydrochloride; 5-AMU HCl
EINECS	Contact for details

Quality Control

Our 5-(Aminomethyl)Pyrimidine-2,4(1H,3H)-Dione Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) documenting purity, related substances, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.