Description

4-Borono-Dl-Phenylalanine B10 Enriched is a specialized, isotopically enriched derivative of phenylalanine, where the boron-10 isotope is incorporated into the boronic acid functional group. This compound is of significant value for its neutron-capturing properties, making it a critical intermediate in the development of Boron Neutron Capture Therapy (BNCT) agents for targeted cancer treatment. It is primarily utilized by advanced pharmaceutical research institutions, radiopharmaceutical developers, and academic laboratories focused on oncology and nuclear medicine.

Application

• Key precursor in the synthesis of Boron Neutron Capture Therapy (BNCT) pharmaceuticals.
• Research and development of targeted radiopharmaceuticals and diagnostic agents.
• Building block for boron-containing amino acid analogs used in biochemical studies.
• Intermediate in the production of neutron capture sensitizers for experimental cancer therapies.
• Used in isotope labeling studies for metabolic pathway tracing.
• Component in pharmaceutical research focusing on tumor-selective drug delivery systems.

Basic Information

Product Name	4-Borono-Dl-Phenylalanine B10 Enriched
CAS No.	90580-64-6
Molecular Formula	C9H12B10NO4
Molecular Weight	~223.01 g/mol (for B10 enriched form)
Synonyms	B10-4-Boronophenylalanine; BPA-B10; DL-4-Boronophenylalanine enriched in Boron-10; B10-BPA; (RS)-2-Amino-3-(4-boronophenyl)propanoic acid (B10); p-Boronophenylalanine-B10; 4-Borono-DL-phenylalanine (Boron-10); NSC 113233 (B10 enriched)
EINECS	Contact for details

Quality Control

Our 4-Borono-Dl-Phenylalanine B10 Enriched is manufactured under strict quality systems to ensure the high purity and isotopic enrichment required for advanced medical research. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as chemical purity, isotopic enrichment (B10%), and impurity profiles. We adhere to cGMP guidelines for the production of pharmaceutical intermediates, ensuring traceability and consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (B10%)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.