Description

4-Chloro-2-Methyl-5,6,7,8-Tetrahydro-Quinazoline is a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its fused bicyclic structure, which serves as a privileged scaffold for constructing complex molecules with targeted biological activity. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used as a core scaffold for developing new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Chemical Biology Probe: Serves as a starting point for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a building block for organic electronic materials and advanced polymers due to its electron-deficient quinazoline core.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	4-Chloro-2-Methyl-5,6,7,8-Tetrahydro-Quinazoline
CAS No.	90561-38-9
Molecular Formula	C9H11ClN2
Molecular Weight	182.65 g/mol
Synonyms	4-Chloro-2-methyl-5,6,7,8-tetrahydroquinazoline; 2-Methyl-4-chloro-5,6,7,8-tetrahydroquinazoline; 5,6,7,8-Tetrahydro-4-chloro-2-methylquinazoline; 4-Chloro-2-methyl-1,2,3,4-tetrahydroquinazoline (tautomer); Quinazoline, 4-chloro-5,6,7,8-tetrahydro-2-methyl-; 90561-38-9 (CAS Registry)
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Methyl-5,6,7,8-Tetrahydro-Quinazoline is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our commitment to traceability and documentation supports your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.