Description

Tyrosyl-Arginyl-Phenylalanyl-Glycine Ethyl Ester is a synthetic tetrapeptide derivative with a C-terminal ethyl ester modification. This compound is of significant interest in pharmaceutical and biochemical research due to its role as a key intermediate or model substrate for studying enzymatic processes, particularly those involving proteases and peptidases. It serves as a crucial building block for researchers and manufacturers in the life sciences sector who require high-purity, well-characterized peptide fragments for drug discovery, diagnostic development, and metabolic studies.

Application

• Pharmaceutical Research Intermediate: Used as a precursor or model compound in the development of novel therapeutic agents, particularly those targeting enzymatic pathways.
• Biochemical Substrate: Serves as a specific substrate for studying the activity, kinetics, and inhibition of proteolytic enzymes like trypsin, chymotrypsin, and other serine proteases.
• Peptide Synthesis Building Block: A key raw material in solid-phase or solution-phase peptide synthesis for constructing larger, more complex peptide sequences.
• Diagnostic Reagent Development: Employed in the formulation of assay kits and reagents for clinical diagnostics and research to detect or quantify enzyme activity.
• Metabolic Pathway Studies: Utilized in research to investigate peptide metabolism, absorption, and stability in biological systems.
• Cosmeceutical R&D: Investigated for potential applications in advanced skincare formulations targeting specific biological pathways.

Basic Information

Product Name	Tyrosyl-Arginyl-Phenylalanyl-Glycine Ethyl Ester
CAS No.	90549-84-1
Molecular Formula	C33H47N9O8
Molecular Weight	697.79 g/mol
Synonyms	YRFG-OEt; Tyr-Arg-Phe-Gly-OEt; H-Tyr-Arg-Phe-Gly-OEt; Tetrapeptide YRFG ethyl ester; L-Tyrosyl-L-arginyl-L-phenylalanylglycine ethyl ester; TAPG ethyl ester; 90549-84-1; Ethyl (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-phenylpropanoyl]amino]acetate
EINECS	Contact for details

Quality Control

Our Tyrosyl-Arginyl-Phenylalanyl-Glycine Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request. We are committed to providing consistent, high-quality materials to support your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.