Description

Boc-D-Cys(Mbzl)-Osu CAS NO 90545-10-1 is a high-purity, protected amino acid derivative widely used as a critical building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring precise stereochemistry and side-chain protection to ensure the fidelity of complex peptide sequences. It is primarily utilized by the pharmaceutical, biotechnology, and life sciences industries for the development of therapeutic peptides, research biochemicals, and novel drug candidates.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of D-cysteine residues into peptide chains.
• Pharmaceutical Research & Development: Used in the synthesis of peptide-based active pharmaceutical ingredients (APIs) and investigational new drugs.
• Bioconjugation and Protein Engineering: Serves as a protected thiol handle for creating site-specific modifications, antibody-drug conjugates (ADCs), or labeled biomolecules.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening and drug discovery.
• Academic and Contract Research: A fundamental reagent for studies in biochemistry, medicinal chemistry, and molecular biology.
• Custom Peptide Manufacturing: An essential raw material for CROs and CDMOs producing bespoke peptides for clients.

Basic Information

Product Name	Boc-D-Cys(Mbzl)-Osu
CAS No.	90545-10-1
Molecular Formula	C20H26N2O7S
Molecular Weight	438.50 g/mol
Synonyms	N-α-(tert-Butoxycarbonyl)-D-cysteine 4-methylbenzyl ester N-succinimidyl ester; Boc-D-cysteine(Mob)-OSu; Boc-D-Cys(4-Me-Bzl)-OSu; (2R)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-[(4-methylphenyl)methanesulfanyl]propanoic acid 2,5-dioxopyrrolidin-1-yl ester; Boc-D-Cys(Mob)-OSu; N-Boc-D-Cys(4-Me-Bzl)-OSu; tert-Butyloxycarbonyl-D-cysteine(4-methylbenzyl)ester N-hydroxysuccinimide ester
EINECS	Contact for details

Quality Control

Our Boc-D-Cys(Mbzl)-Osu is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) with full traceability are provided to guarantee consistent quality, reliability, and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.