Description

n-(3-Aminopropyl)Glycine Dihydrochloride is a high-purity, bifunctional organic building block featuring both amino and carboxylic acid groups. This compound is essential for researchers and manufacturers requiring a versatile linker molecule for peptide synthesis, bioconjugation, and the development of novel chemical entities. It is particularly valuable for the pharmaceutical, biotechnology, and life science research sectors, where precise molecular assembly is critical.

Application

• Peptide Synthesis: Serves as a specialized spacer or linker amino acid in solid-phase and solution-phase peptide synthesis to introduce specific functional handles.
• Bioconjugation Reagent: Used to crosslink biomolecules (e.g., proteins, antibodies) to other molecules, surfaces, or nanoparticles for diagnostic and therapeutic applications.
• Pharmaceutical Intermediates: A key raw material in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, particularly those requiring a flexible aminopropyl chain.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme activity, protein-protein interactions, and cellular processes.
• Material Science: Acts as a monomer or functionalization agent for creating specialized polymers, hydrogels, and surface coatings with amine functionality.
• Chelating Agent Precursor: Used in the synthesis of chelating ligands for metal ions, applicable in catalysis, imaging, and metal sequestration.

Basic Information

Product Name	n-(3-Aminopropyl)Glycine Dihydrochloride
CAS No.	90495-95-7
Molecular Formula	C5H12N2O2 · 2HCl
Molecular Weight	209.09 g/mol
Synonyms	3-[(Aminoethyl)amino]propanoic Acid Dihydrochloride; 3-(2-Aminoethylamino)propionic Acid Dihydrochloride; (3-Aminopropyl)Glycine 2HCl; N-(2-Aminoethyl)-β-alanine Dihydrochloride; 2-(2-Aminoethylamino)ethanecarboxylic Acid Dihydrochloride; β-Alanine, N-(2-aminoethyl)-, dihydrochloride; AEEA-Glycine 2HCl
EINECS	Contact for details

Quality Control

Our n-(3-Aminopropyl)Glycine Dihydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and production. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.