Description

Pancreatic Polypeptide, Rat CAS NO 90419-12-8 is a 36-amino acid peptide hormone produced by the pancreatic islets. This compound is a critical research tool for studying endocrine regulation, particularly in relation to appetite, energy homeostasis, and gastrointestinal function. It is essential for researchers and developers in the fields of metabolic disease research, neuroendocrinology, and preclinical pharmaceutical development.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating pancreatic function, hormone interactions, and metabolic pathways.
• Endocrinology Studies: Critical for in vitro and in vivo research on the role of pancreatic polypeptide in regulating pancreatic and gastrointestinal secretions.
• Metabolic Disease Models: Applied in preclinical research for obesity, diabetes, and related metabolic disorders to understand satiety signaling and energy balance.
• Antibody Production & Immunoassays: Serves as an antigen for generating specific antibodies used in ELISA, RIA, and immunohistochemistry applications.
• Neuroscience Research: Utilized to study the central nervous system effects of pancreatic polypeptide and its impact on brain-gut axis communication.
• Pharmaceutical Development: Acts as a lead compound or reference molecule in the discovery and development of novel therapeutics targeting Y4/Y5 receptors.

Basic Information

Product Name	Pancreatic Polypeptide, Rat
CAS No.	90419-12-8
Molecular Formula	C185H283N55O55S
Molecular Weight	4221.7 g/mol
Synonyms	Rat Pancreatic Polypeptide; rPP; PYY (Pancreatic Peptide YY); PPY; Pancreatic Propeptide; NPY (related); PP-fold peptide; Pancreatic Hormone PP; 36-AA Pancreatic Peptide; PP1 (Rat)
EINECS	Contact for details

Quality Control

Our Pancreatic Polypeptide, Rat is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. We provide full traceability and Certificates of Analysis (COA) are available for all research and development purposes, ensuring compliance with rigorous standards for biochemical reagents.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under inert atmosphere. Allow the vial to reach room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.