Description

3-Chloro-5-Fluorobenzaldehyde is a versatile halogenated benzaldehyde derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the chloro-fluoro substitution pattern enhances biological activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a core building block for synthesizing fluorinated liquid crystal compounds and organic light-emitting diode (OLED) materials, contributing to improved electronic properties.
• Functional Dye & Pigment Manufacturing: Employed in the creation of specialized dyes and pigments, where its structure helps achieve specific color fastness and light stability.
• Cross-Coupling Reactions: An essential substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for constructing biaryl systems common in many advanced materials.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	3-Chloro-5-Fluorobenzaldehyde
CAS No.	90390-49-1
Molecular Formula	C7H4ClFO
Molecular Weight	158.56 g/mol
Synonyms	3-Chloro-5-fluorobenzaldehyde; 5-Fluoro-3-chlorobenzaldehyde; Benzaldehyde, 3-chloro-5-fluoro-; 3-Chloro-5-fluorobenzenecarboxaldehyde; m-Chloro-m-fluorobenzaldehyde; 90390-49-1; 3-Cl-5-F-BzH
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Fluorobenzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	45 - 50 °C
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.