Description

3,5-Difluorobenzylamine is a versatile fluorinated aromatic amine building block of significant importance in advanced organic synthesis. Its value lies in the unique reactivity of the benzylamine group combined with the electronic effects of the meta-positioned fluorine atoms, enabling precise molecular construction. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of modern herbicides, fungicides, and insecticides, where the difluoro motif can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Incorporated into polymers and advanced resins to modify thermal stability, chemical resistance, and surface properties.
• Fluorescent Dye and Sensor Chemistry: Utilized in the synthesis of fluorophores and molecular probes for bio-imaging and diagnostic applications.
• Peptidomimetics and Bio-conjugation: The amine functionality allows for its use in constructing peptide analogs and for linking molecules in bioconjugation strategies.

Basic Information

Product Name	3,5-Difluorobenzylamine
CAS No.	90390-27-5
Molecular Formula	C7H7F2N
Molecular Weight	143.13 g/mol
Synonyms	(3,5-Difluorophenyl)methanamine; 3,5-Difluorobenzylamine; 1-(3,5-Difluorophenyl)methanamine; 3,5-Difluoro-benzenemethanamine; Benzenemethanamine, 3,5-difluoro-; α-Amino-3,5-difluorotoluene; 3,5-Difluorophenylmethylamine
EINECS	Contact for details

Quality Control

Our 3,5-Difluorobenzylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for fine chemical intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.