Description

Benzenemethanamine, n-(1-Methylethyl)-3-(Trifluoromethyl)- is a specialized aromatic amine derivative, distinguished by its trifluoromethyl and isopropylamino substituents, which confer unique chemical reactivity and physical properties. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in the synthesis of complex organic molecules. It is essential for R&D and production in the pharmaceutical, agrochemical, and specialty chemical industries, where its structural motifs are leveraged to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic areas.
• Agrochemical Synthesis: Used as a precursor in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Employed in organometallic chemistry and catalysis research to create novel ligands for transition metal complexes.
• Material Science Research: Serves as a monomer or functionalization agent in the synthesis of specialty polymers, coatings, and advanced organic materials.
• Fluorine Chemistry Building Block: Utilized in medicinal and synthetic chemistry to introduce the pharmacologically valuable trifluoromethyl group into target molecules.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and contract research organizations (CROs/CMOs) serving the life sciences sector.

Basic Information

Product Name	Benzenemethanamine, n-(1-Methylethyl)-3-(Trifluoromethyl)-
CAS No.	90390-08-2
Molecular Formula	C11H14F3N
Molecular Weight	217.23 g/mol
Synonyms	α-[(1-Methylethyl)amino]-3-(trifluoromethyl)benzenemethane; 1-[3-(Trifluoromethyl)phenyl]-N-isopropylmethanamine; N-Isopropyl-1-[3-(trifluoromethyl)phenyl]methanamine; 3-(Trifluoromethyl)benzylisopropylamine; N-[(3-Trifluoromethyl)benzyl]isopropylamine; N-Isopropyl-α-methyl-3-(trifluoromethyl)benzylamine; (3-Trifluoromethylphenyl)methylisopropylamine
EINECS	Contact for details

Quality Control

Our Benzenemethanamine, n-(1-Methylethyl)-3-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and batch-to-batch consistency suitable for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support compliance with REACH, FDA guidelines for intermediates, and cGMP standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Individual Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.