Description

5-Fluoro-2-(Trifluoromethyl)Benzaldehyde is a high-value fluorinated aromatic aldehyde building block, prized for its unique electronic and steric properties imparted by the fluorine and trifluoromethyl substituents. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its structure is key to modulating biological activity and metabolic stability. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity, stability, and uptake in target organisms.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers where fluorinated aromatic units are required.
• Custom Synthesis & Contract Manufacturing: A key building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Fluoro-2-(Trifluoromethyl)Benzaldehyde
CAS No.	90381-08-1
Molecular Formula	C8H4F4O
Molecular Weight	192.11 g/mol
Synonyms	5-Fluoro-α,α,α-trifluoro-o-tolualdehyde; 2-(Trifluoromethyl)-5-fluorobenzaldehyde; 5-Fluoro-2-trifluoromethylbenzaldehyde; 5-Fluoro-α,α,α-trifluoro-2-methylbenzaldehyde; 90381-08-1; Benzaldehyde, 5-fluoro-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(Trifluoromethyl)Benzaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically meeting standards for research and commercial synthesis. Every lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to support regulatory filings for our customers in advanced markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.