Description

tert-Butyloxycarbonyl-Arginylproline-2-Naphthylamide CAS NO 90375-78-3 is a protected peptide derivative, specifically a Boc-Arg-Pro-2-Naphthylamide, serving as a crucial synthetic intermediate and research tool. This compound is valued for its role in peptide synthesis and as a potential substrate for studying enzymatic activity, particularly for proteases like dipeptidyl peptidase. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing novel therapeutic agents and biochemical assays.

Application

• Pharmaceutical Intermediate: Key building block in the solid-phase and solution-phase synthesis of complex peptide-based drugs and bioactive molecules.
• Biochemical Research: Used as a specialized substrate or inhibitor in enzymatic studies, particularly for protease and peptidase activity assays.
• Proteomics & Diagnostics: Employed in the development of diagnostic kits and research tools for detecting specific enzyme activities in biological samples.
• Academic Research: A valuable reagent for universities and research institutes studying peptide chemistry, enzyme kinetics, and signal transduction pathways.
• Fine Chemical Synthesis: Serves as a precursor for the preparation of more complex, labeled, or conjugated peptides for various applications.

Basic Information

Item	Details
Product Name	tert-Butyloxycarbonyl-Arginylproline-2-Naphthylamide
CAS No.	90375-78-3
Molecular Formula	C26H39N7O5
Molecular Weight	529.64 g/mol
Synonyms	Boc-Arg-Pro-2-Naphthylamide; Boc-L-Arginyl-L-proline 2-naphthylamide; Nα-Boc-L-arginyl-L-proline β-naphthylamide; BOC-Arg-Pro-2NA; tert-Butoxycarbonylarginylproline β-naphthylamide; L-Arginine, N2-[N-[(1,1-dimethylethoxy)carbonyl]-L-prolyl]-, 1-(2-naphthalenylmethyl) ester; (S)-2-((S)-5-((Tert-butoxycarbonyl)amino)-2-guanidinopentanamido)-1-(naphthalen-2-ylmethyl)pyrrolidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyloxycarbonyl-Arginylproline-2-Naphthylamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.