Description

4-Chloro-5-Methyl-7H-Pyrrolo[2,3-D]Pyrimidin-2-Amine is a high-purity heterocyclic building block of significant importance in modern pharmaceutical and agrochemical research. This compound serves as a critical intermediate for the synthesis of novel, biologically active molecules, particularly kinase inhibitors. It is primarily sought after by research and development teams in the pharmaceutical, biotechnology, and agrochemical sectors for lead optimization and process development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted small-molecule drugs, especially protein kinase inhibitors for oncology and inflammatory diseases.
• Agrochemical Research: Used as a building block for developing new active ingredients in crop protection products.
• Biochemical Tool Compound: Serves as a core scaffold for creating probes and inhibitors to study specific biological pathways in academic and industrial research.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development programs for global clients.

Basic Information

Product Name	4-Chloro-5-Methyl-7H-Pyrrolo[2,3-D]Pyrimidin-2-Amine
CAS No.	90358-16-0
Molecular Formula	C7H7ClN4
Molecular Weight	182.61 g/mol
Synonyms	2-Amino-4-chloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-ylamine; 5-Methyl-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine; 90358-16-0; Pyrrolo[2,3-d]pyrimidine, 4-chloro-5-methyl-7H-, 2-amino-; 4-Chloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Methyl-7H-Pyrrolo[2,3-D]Pyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.