Description

(D(Ch2)(5/1),D-Tyr(Et)2,Val4,Arg8,Des-Gly9)-Vasopressin is a synthetic, modified analogue of the neurohypophysial hormone vasopressin, designed for enhanced receptor selectivity and metabolic stability. This compound is of significant value for advanced pharmacological research, particularly in the study of vasopressin receptor subtypes V1a, V1b, and V2. It serves as a critical research tool for scientists and developers in the pharmaceutical and biotechnology sectors, enabling the exploration of novel therapeutics for conditions related to fluid balance, cardiovascular function, and central nervous system disorders.

Application

• Pharmacological Research: As a selective ligand for investigating the structure-activity relationships (SAR) of vasopressin receptor subtypes.
• Drug Discovery & Development: A key intermediate or reference standard in the development of novel peptide-based therapeutics targeting vasopressin pathways.
• Biochemical Assays: Used in receptor binding studies, functional assays (e.g., cAMP accumulation, calcium mobilization), and antagonist/agonist characterization.
• Neuroscience Studies: Research into the role of vasopressin in social behavior, stress response, memory, and autonomic regulation.
• Cardiovascular Research: Investigation of vasopressin's effects on vascular tone, blood pressure regulation, and cardiac function.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in peptide synthesis and analysis.

Basic Information

Item	Detail
Product Name	(D(Ch2)(5/1),D-Tyr(Et)2,Val4,Arg8,Des-Gly9)-Vasopressin
CAS No.	90332-82-4
Molecular Formula	C52H78N16O12S2
Molecular Weight	1151.4 g/mol
Synonyms	Deamino-[D-2-O-ethyltyrosine,valine4,arginine8]-vasopressin; d(CH2)5[D-Tyr(Et)2,Val4,Arg8,des-Gly9]VP; SK&F 101926; Vasopressin V1a receptor antagonist; [1-(β-Mercapto-β,β-cyclopentamethylenepropionic acid),2-(O-ethyl-D-tyrosine),4-valine,8-arginine]vasopressin; Desmopressin analogue; Selective V1a antagonist.
EINECS	Contact for details

Quality Control

Our (D(Ch2)(5/1),D-Tyr(Et)2,Val4,Arg8,Des-Gly9)-Vasopressin is manufactured under strict quality systems suitable for research applications. Each batch undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications and test results are available upon request to ensure full traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.