Description

β-Mercapto-Beta,β-Cyclopentamethylene-Propionyl-Tyr(Et)-Phe-Val-Asn-Cys-Pro-Arg-Nh2 CAS NO 90332-81-3 is a synthetic peptide derivative of significant interest in advanced pharmaceutical research and development. Its complex structure, featuring a β-mercapto cyclopentamethylene moiety, makes it a valuable intermediate for creating novel therapeutic agents, particularly in the fields of endocrinology and targeted drug delivery. This high-purity compound is essential for researchers and manufacturers developing next-generation peptide-based pharmaceuticals and diagnostic tools.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel peptide drugs and hormone analogs.
• Research & Development: Used in academic and industrial R&D for studying peptide structure-activity relationships (SAR) and receptor binding.
• Protease Inhibitor Development: Potential application in the design of enzyme inhibitors due to its modified cysteine (Cys) residue.
• Conjugation Chemistry: The β-mercapto group provides a handle for site-specific bioconjugation, useful in creating antibody-drug conjugates (ADCs) or peptide-drug conjugates.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in peptide manufacturing.

Basic Information

Product Name	β-Mercapto-Beta,β-Cyclopentamethylene-Propionyl-Tyr(Et)-Phe-Val-Asn-Cys-Pro-Arg-Nh2
CAS No.	90332-81-3
Molecular Formula	C58H86N14O13S
Molecular Weight	1211.5 g/mol
Synonyms	β-Mercapto-β,β-cyclopentamethylenepropionyl-Tyr(Et)-Phe-Val-Asn-Cys-Pro-Arg-amide; [Cys(β-Mpa)]-Peptide derivative; Mpa-Tyr(Et)-Phe-Val-Asn-Cys-Pro-Arg-NH2; Cyclic thioether peptide intermediate; Mercaptocyclopentylpropionyl octapeptide amide; CAS 90332-81-3
EINECS	Contact for details

Quality Control

This peptide is manufactured under strict cGMP (current Good Manufacturing Practice) guidelines to ensure the highest standards of purity and consistency for research and pharmaceutical applications. Every batch is subjected to comprehensive analytical characterization, including HPLC for purity and MS for identity confirmation. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) and easily oxidized nature, store the product under an inert atmosphere (e.g., argon or nitrogen) at a controlled temperature of -20°C or below. For long-term storage, desiccants are recommended. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.