Description

(Z)-Ethyl 2-Methyl-4-Oxobut-2-Enoate is a versatile α,β-unsaturated ester building block, prized for its reactive enone and ester functionalities. This compound is essential for facilitating advanced organic synthesis, enabling the construction of complex molecular frameworks with high precision. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in Michael additions, cyclizations, and as a key chiral intermediate.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing chiral centers or heterocyclic structures.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, leveraging its reactivity to create novel bioactive compounds.
• Fine Chemical Manufacturing: Acts as a key building block for fragrances, flavors, and specialty polymers where specific stereochemistry is required.
• Academic & Industrial R&D: Employed in methodological development and discovery chemistry for novel reaction pathways and catalysis studies.
• Material Science: Investigated as a monomer or cross-linking agent for specialized polymer networks with tailored properties.

Basic Information

Product Name	(Z)-Ethyl 2-Methyl-4-Oxobut-2-Enoate
CAS No.	90177-86-9
Molecular Formula	C7H10O3
Molecular Weight	142.15 g/mol
Synonyms	(Z)-Ethyl 2-Methyl-4-oxobut-2-enoate; Ethyl (Z)-2-Methyl-4-oxo-2-butenoate; (Z)-2-Methyl-4-oxo-2-butenoic Acid Ethyl Ester; Ethyl (Z)-2-Methylacetoacetate (enol form); (Z)-Ethyl 2-Methyl-4-oxobut-2-enoate; (Z)-Ethyl 2-Methyl-4-oxo-2-butenoate; 2-Butenoic acid, 2-methyl-4-oxo-, ethyl ester, (2Z)-
EINECS	Contact for details

Quality Control

Our (Z)-Ethyl 2-Methyl-4-Oxobut-2-Enoate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (Z-isomer)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.