Description

4-Fluoro-2-(Trifluoromethyl)Benzaldehyde is a high-value fluorinated aromatic aldehyde building block essential for advanced organic synthesis. This compound is prized for its unique electronic properties imparted by the fluorine and trifluoromethyl substituents, which are critical for modulating the reactivity and physical characteristics of target molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved performance and durability.
• Functional Polymer Monomer: Incorporated into specialty polymers to impart specific properties such as chemical resistance, thermal stability, and low surface energy.
• Cross-Coupling Reactions: The aldehyde group acts as a versatile handle for further functionalization via reactions like Suzuki, Heck, or reductive amination.
• Fluorine Chemistry Research: An important reagent for academic and industrial research exploring new methodologies in organofluorine chemistry.

Basic Information

Product Name	4-Fluoro-2-(Trifluoromethyl)Benzaldehyde
CAS No.	90176-80-0
Molecular Formula	C8H4F4O
Molecular Weight	192.11 g/mol
Synonyms	4-Fluoro-2-(trifluoromethyl)benzaldehyde; 2-Trifluoromethyl-4-fluorobenzaldehyde; 4-Fluoro-alpha,alpha,α-trifluoro-o-tolualdehyde; 4-Fluoro-2-trifluoromethylbenzaldehyde; 90176-80-0; Benzaldehyde, 4-fluoro-2-(trifluoromethyl)-; o-Trifluoromethyl-p-fluorobenzaldehyde
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-(Trifluoromethyl)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP, ICH Q7, and REACH regulations for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.