Description

(+/-)-Clopidogrel Hydrochloride CAS NO 90055-48-4 is a key pharmaceutical intermediate and the racemic form of the widely used antiplatelet agent. This compound is of critical importance for research, development, and the synthesis of active pharmaceutical ingredients (APIs) targeting cardiovascular diseases. It is primarily needed by pharmaceutical manufacturers, R&D laboratories, and fine chemical suppliers engaged in producing or investigating antithrombotic therapies.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of Clopidogrel bisulfate, the active ingredient in antiplatelet medications.
• Research & Development: Serves as a critical reference standard and starting material for pharmacological studies and new drug development in cardiovascular research.
• Process Chemistry: Used in method development and optimization for the industrial-scale production of Clopidogrel and its derivatives.
• Analytical Standard: Employed as a high-purity standard in HPLC, LC-MS, and other analytical methods for quality control and impurity profiling.
• Chiral Resolution Studies: Essential for studies focusing on the separation of the enantiomers to produce the therapeutically active S-isomer.
• Generic Drug Manufacturing: A vital raw material for companies producing generic versions of antiplatelet drugs.

Basic Information

Product Name	(+/-)-Clopidogrel Hydrochloride
CAS No.	90055-48-4
Molecular Formula	C16H16ClNO2S•HCl
Molecular Weight	374.29 g/mol (for hydrochloride salt)
Synonyms	Clopidogrel HCl (Racemic); Methyl (RS)-α-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetate hydrochloride; SR 25989; PCR 4099 Hydrochloride; (±)-Clopidogrel Hydrochloride; Clopidogrel Racemate Hydrochloride; 2-(2-Chlorophenyl)-2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)acetic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our (+/-)-Clopidogrel Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for assay and impurity profile, to ensure it meets high-purity standards suitable for pharmaceutical R&D and intermediate synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, residual solvents, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.