Description

1-Benzothiophene-2-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its role as a versatile sulfonylation reagent, enabling the efficient introduction of the benzothiophene-2-sulfonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of biologically active molecules, including potential kinase inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides that incorporate the benzothiophene scaffold.
• Material Science Research: Building block for creating novel polymers, dyes, and organic electronic materials with specific sulfonated properties.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes for studying enzyme function and protein labeling.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	1-Benzothiophene-2-Sulfonyl Chloride
CAS No.	90001-64-2
Molecular Formula	C8H5ClO2S2
Molecular Weight	232.70 g/mol
Synonyms	Benzo[b]thiophene-2-sulfonyl chloride; 2-Benzothiophenesulfonyl chloride; 1-Benzothiophene-2-sulfonyl chloride; 2-Thianaphthenesulfonyl chloride; Benzothiophene-2-sulfonyl chloride; BTS-Cl; 2-Sulfonylchloride benzothiophene
EINECS	Contact for details

Quality Control

Our 1-Benzothiophene-2-Sulfonyl Chloride is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.