Description

Insulin-Dextran is a chemically modified insulin conjugate where the protein is covalently linked to a dextran polymer. This product is engineered to enhance the stability and prolong the circulating half-life of insulin, making it a critical tool for advanced pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the biopharmaceutical sector focusing on novel drug delivery systems and therapeutic protein stabilization.

Application

• Pharmaceutical Research: Used as a model conjugate in studying the pharmacokinetics and biodistribution of protein-polymer therapeutics.
• Drug Delivery System Development: Serves as a key component in the design of sustained-release insulin formulations.
• Bioconjugation Studies: Acts as a reference standard for developing and validating conjugation techniques between proteins and polysaccharides.
• Stability Enhancement: Employed to investigate methods for improving the physical and chemical stability of peptide and protein-based drugs.
• Immunology Research: Used in studies exploring the immunogenicity and antigenicity of modified therapeutic proteins.
• Analytical Method Development: Functions as a well-defined conjugate for calibrating analytical instruments like HPLC and SEC.

Basic Information

Product Name	Insulin-Dextran
CAS No.	9083-89-0
Molecular Formula	Contact for details
Molecular Weight	Variable (Polymer Conjugate)
Synonyms	Dextran-Insulin Conjugate; Insulin Dextran Complex; Insulin-Dextran Conjugate; Dextran Insulin; Insulin Modified Dextran; Insulin-Dextran Adduct; Protein-Polysaccharide Conjugate
EINECS	Contact for details

Quality Control

Our Insulin-Dextran is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and conjugate ratio consistency. Certificates of Analysis (COA) detailing specifications such as protein content, dextran linkage, and impurity profiles are available upon request to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms
Protein Content (Insulin)	Contact for details
Dextran Content	Contact for details
Conjugation Ratio	Contact for details
Purity (HPLC)	≥ 95%
Water Content	≤ 5.0%
Biological Activity	Assayed

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.