Description

Tuftsin is a naturally occurring immunostimulatory tetrapeptide with the sequence Thr-Lys-Pro-Arg. This compound matters for its significant role in modulating the immune system by specifically stimulating the phagocytic activity of macrophages, neutrophils, and monocytes. It is primarily needed by researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on immunology, vaccine development, and therapeutic peptide synthesis.

Application

• Immunological Research: Used as a standard and tool compound for studying macrophage activation, phagocytosis, and immune response modulation.
• Pharmaceutical Development: Serves as a lead compound or active pharmaceutical ingredient (API) in the development of immunotherapies and immunomodulatory drugs.
• Vaccine Adjuvants: Investigated for its potential to enhance the efficacy of vaccines by boosting the innate immune response.
• Cell Culture & In Vitro Studies: Employed in cell-based assays to stimulate immune cells and study downstream signaling pathways.
• Peptide Synthesis: Used as a building block or reference standard in custom peptide synthesis for research and diagnostic applications.
• Anti-infective Research: Explored for its role in enhancing the body's defense against bacterial, fungal, and parasitic infections.

Basic Information

Product Name	Tuftsin
CAS No.	9063-57-4
Molecular Formula	C20H37N7O6
Molecular Weight	495.56 g/mol
Synonyms	L-Threonyl-L-lysyl-L-prolyl-L-arginine; Thr-Lys-Pro-Arg; Tuftsin (human); Immunostimulant peptide tuftsin; H-Thr-Lys-Pro-Arg-OH; Tetrapeptide Thr-Lys-Pro-Arg; Tuftsin peptide; IgG-derived phagocytosis stimulating peptide
EINECS	Contact for details

Quality Control

Our Tuftsin is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade standards suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.