Description

Hemoglobin J Baltimore is a specific variant of hemoglobin, a vital oxygen-transporting metalloprotein found in red blood cells. This product is of significant interest for biochemical research and diagnostic development due to its unique structural and functional properties. It is primarily utilized by researchers in biochemistry, hematology, and clinical diagnostics for studying hemoglobinopathies, developing analytical standards, and investigating oxygen-binding kinetics.

Application

• Biochemical Research Standard: Serves as a reference material for the study of hemoglobin structure, function, and genetic variants.
• Clinical Diagnostics Development: Used in the development and calibration of diagnostic assays for detecting hemoglobin disorders like thalassemia and sickle cell disease.
• Hematology Studies: Essential for in-vitro research on oxygen transport, erythrocyte function, and blood-related pathologies.
• Pharmaceutical Research: Employed in preclinical studies for drugs targeting hemoglobin or red blood cell disorders.
• Educational & Training Material: Used in academic and laboratory training settings to teach principles of protein chemistry and molecular biology.
• Quality Control Reagent: Acts as a control substance in the quality assurance processes for clinical laboratory equipment and reagents.

Basic Information

Product Name	Hemoglobin J Baltimore
CAS No.	9034-86-0
Molecular Formula	Contact for details
Molecular Weight	~64,500 Da (for tetramer)
Synonyms	Hb J Baltimore; Hemoglobin variant J Baltimore; α-2 16(A14) Lys→Asn, β-2; HBA2; Oxyhemoglobin J Baltimore; Deoxyhemoglobin J Baltimore; Methemoglobin J Baltimore
EINECS	Contact for details

Quality Control

Our Hemoglobin J Baltimore is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and purity suitable for research applications. Each lot is characterized using advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and functional activity is provided with every shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (IR/Spectrophotometry)	Conforms
Purity (HPLC/Electrophoresis)	≥ 95% (Hb J Baltimore)
Protein Concentration (UV-Vis)	As per COA
Methemoglobin Content	< 5%
Hemichrome Content	< 2%
Oxygen Affinity (p50)	Contact for details
Biological Activity	Functional oxygen binding
Endotoxin	< 1.0 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.