Description

Hemoglobin G Philadelphia is a specific variant of hemoglobin, a critical oxygen-transporting metalloprotein found in red blood cells. This product is essential for biochemical research, diagnostic development, and the study of hemoglobinopathies and related blood disorders. It is primarily utilized by research institutions, diagnostic manufacturers, and pharmaceutical companies engaged in hematology and clinical chemistry.

Application

• Biochemical Research: Used as a standard or substrate in studies investigating hemoglobin structure, function, and oxygen-binding kinetics.
• Diagnostic Development: Serves as a key component in the calibration and validation of clinical analyzers and diagnostic kits for blood gas analysis and hemoglobin testing.
• Hematology Studies: Employed in research focused on sickle cell disease, thalassemias, and other hemoglobin variants to understand disease mechanisms.
• Pharmaceutical R&D: Acts as a model compound in the development of therapeutic agents targeting hemoglobin disorders.
• Educational Reference: Used in academic and teaching laboratories to demonstrate protein chemistry and genetic principles.
• Quality Control: Functions as a reference material in the quality assurance processes of clinical laboratories.

Basic Information

Product Name	Hemoglobin G Philadelphia
CAS No.	9034-74-6
Molecular Formula	C2952H4664N812O832S8Fe4
Molecular Weight	~64,500 Da (for tetramer)
Synonyms	Hb G Philadelphia; Hemoglobin variant G Philadelphia; α268(E17)Asn→Lysβ2; Hemoglobin α-G Philadelphia; Hemoglobin G-Philadelphia; Hemoglobin G Philly; Hb G-Phil; Contact for details on additional synonyms.
EINECS	Contact for details

Quality Control

Our Hemoglobin G Philadelphia is produced and handled under stringent quality protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the exacting standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, spectral properties, and functional characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. Handle under appropriate laboratory conditions.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (IR / UV-Vis)	Conforms to standard
Purity (HPLC)	≥ 95% (Hb G Philadelphia)
Assay (Spectrophotometric)	As per COA
Methemoglobin Content	< 5%
Solubility	Clear solution in buffer
Endotoxin	< 1.0 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.