Description

β-Melanotrophin, also known as β-melanocyte-stimulating hormone (β-MSH), is a linear tridecapeptide hormone derived from proopiomelanocortin (POMC). This compound plays a crucial role in the regulation of skin pigmentation and energy homeostasis by stimulating melanogenesis in melanocytes. It is primarily utilized in advanced biochemical research and pharmaceutical development. Key industries requiring this high-purity peptide include academic and industrial research laboratories, as well as companies developing diagnostic assays and novel therapeutic agents.

Application

• Biomedical Research: Fundamental studies on melanocortin receptor (MCR) signaling pathways, particularly MC1R and MC4R.
• Pharmaceutical R&D: As a reference standard or active ingredient in the development of drugs targeting pigmentation disorders, obesity, and metabolic syndromes.
• Diagnostic Development: Used in the production of immunoassays and ELISA kits for the quantitative measurement of related hormones or for antibody characterization.
• Cell Culture & In Vitro Studies: Application in cell-based assays to study its effects on melanocyte proliferation, differentiation, and melanin production.
• Neuroscience Research: Investigation of its role in the central nervous system concerning appetite suppression and neuroprotective effects.
• Cosmeceutical Research: Evaluation of mechanisms related to skin tanning and photoprotection for potential cosmetic applications.

Basic Information

Product Name	β-Melanotrophin
CAS No.	9034-42-8
Molecular Formula	C₇₇H₁₀₉N₂₁O₁₉S
Molecular Weight	1664.9 g/mol
Synonyms	β-Melanocyte-Stimulating Hormone; β-MSH; β-Melanotropin; β-Melanocyte Stimulating Hormone; β-Melanophorin; β-Intermedin; β-Lipotropin (92-104); H-Asp-Ser-Gly-Pro-Tyr-Lys-Met-Glu-His-Phe-Arg-Trp-Gly-OH; β-LPH (92-104)
EINECS	Contact for details

Quality Control

Our β-Melanotrophin is produced and tested under stringent quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and biological activity, meeting the exacting standards required for research and development. Certificates of Analysis (COA) detailing results for purity (HPLC), peptide content, amino acid analysis, and mass spectrometry (MS) are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Biological Activity	Assayed in vitro (Available on COA)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.