Description

Crotoxin From Crotalus Durissus Terrific is a potent neurotoxic phospholipase A2 complex isolated from the venom of the South American rattlesnake. This high-purity biological toxin is a critical research tool for studying neuromuscular transmission, ion channel function, and the mechanisms of neurotoxicity. It is essential for pharmaceutical R&D, toxicology studies, and the development of novel antivenoms and therapeutic agents. Researchers and manufacturers in the biotechnology, pharmacology, and life sciences sectors rely on this well-characterized compound for its specific biological activity.

Application

• Neuroscience Research: A key tool for investigating presynaptic neurotoxicity, neurotransmitter release, and the function of voltage-gated ion channels.
• Pharmacological Studies: Used in the development and screening of potential antivenom therapies and neuroprotective agents.
• Toxicology & Safety Assessment: Employed as a reference standard in studies of snake venom toxicity and mechanism of action.
• Biochemical Research: Serves as a model phospholipase A2 enzyme for studying protein structure, enzyme kinetics, and membrane interactions.
• Diagnostic Development: Utilized in the production of antibodies and assays for the detection of crotoxin and related neurotoxins.

Basic Information

Product Name	Crotoxin From Crotalus Durissus Terrific
CAS No.	9007-40-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Crotalus Toxin; Crotoxin Complex; Crotalus durissus terrificus Venom Toxin; β-Neurotoxin; Phospholipase A2 Neurotoxin; Crotactin; South American Rattlesnake Toxin; Presynaptic Neurotoxin
EINECS	Contact for details

Quality Control

Our Crotoxin is produced and handled under stringent conditions to ensure batch-to-batch consistency and biological activity. Each lot is characterized using advanced analytical techniques, including HPLC for purity assessment and biological assays to confirm specific neurotoxic activity. A comprehensive Certificate of Analysis (COA) detailing purity, potency, and analytical results is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature before opening to minimize moisture condensation. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Protein Content (Biuret)	≥ 90%
Biological Activity (LD50 assay)	Reported per COA
Endotoxin Level (LAL)	< 10 EU/mg
Solubility	Soluble in water or saline

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.