Description

Antistreptolysin O (ASO) is a purified, standardized enzyme reagent derived from streptococcal bacteria, primarily used as a critical diagnostic tool. It matters because it enables the specific and accurate detection of antibodies against streptolysin O, a key virulence factor, in human serum. This product is essential for clinical diagnostics and research laboratories conducting tests for post-streptococcal sequelae, such as rheumatic fever and glomerulonephritis. Our high-purity grade ensures reliable and reproducible results in immunoturbidimetric and latex agglutination assays.

Application

• Clinical Diagnostics: Primary reagent for the quantitative and qualitative determination of Anti-Streptolysin O (ASO) antibodies in human serum or plasma.
• Immunoturbidimetric Assays: Used as a calibrated antigen in automated analyzers for precise, high-throughput ASO titer measurement.
• Latex Agglutination Tests: Serves as the sensitizing antigen coated onto latex particles for rapid semi-quantitative slide tests.
• Medical Research: Vital tool in immunological studies investigating host response to Group A Streptococcus (GAS) infections.
• Assay Development & Calibration: Used as a reference standard for the development and validation of new in-vitro diagnostic (IVD) kits and methods.
• Epidemiological Studies: Supports population-level screening and monitoring of streptococcal infection rates and immune status.
• Quality Control: Employed as a control material in diagnostic laboratories to ensure the accuracy and precision of ASO testing procedures.

Basic Information

Product Name	Antistreptolysin O
CAS No.	9006-92-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	ASO; Anti-streptolysin O; Streptolysin O; Streptolysin O Antigen; ASO Antigen; Streptococcal exotoxin O; SLO; EC 3.1.4.1; ASO Reagent; ASO Latex Reagent; ASO Turbidimetric Reagent
EINECS	Contact for details

Quality Control

Our Antistreptolysin O is manufactured under strict quality management systems. Each lot undergoes rigorous analytical testing to ensure high specificity, optimal reactivity, and batch-to-batch consistency for diagnostic applications. Quality parameters include immunological identity, potency (titer), and purity assessments. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at 2-8°C. Avoid repeated freeze-thaw cycles. Keep the reagent under the recommended storage conditions to maintain stated potency and performance throughout its shelf life.

Specification

Item	Specification
Appearance	Lyophilized powder or clear solution
Identification (Immunological)	Conforms
Potency (Titer)	Defined per batch (IU/mL)
Purity (HPLC/SDS-PAGE)	≥ 95%
pH	6.5 - 7.5 (in solution)
Endotoxin	< 1.0 EU/mL
Sterility (for specific grades)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.