Description

Dalanated Insulin CAS NO 9004-12-0 is a chemically modified form of the polypeptide hormone insulin, where the terminal alanine residue has been specifically removed. This modification is critical for research into insulin's structure-activity relationships and its metabolic pathways. It serves as a key intermediate and reference standard in advanced pharmaceutical development and biochemical research. This product is essential for laboratories and manufacturers focused on diabetes research, novel therapeutic agent development, and high-purity biochemical synthesis.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control and analytical method development in insulin and biosimilar production.
• Biochemical Research: Employed in studies investigating the impact of specific amino acid residues on insulin's receptor binding affinity, stability, and biological activity.
• Metabolic Pathway Analysis: Serves as a tool in metabolic studies to trace and understand the degradation and processing pathways of modified insulin variants.
• Peptide Synthesis Intermediate: Acts as a starting material or intermediate for the chemical synthesis of novel insulin analogs and related peptide conjugates.
• Diagnostic Reagent Development: Utilized in the development and calibration of immunoassays and other diagnostic tests designed to detect specific insulin isoforms.
• Academic & Institutional Research: Supports fundamental research in endocrinology, molecular biology, and protein engineering within university and government laboratories.

Basic Information

Product Name	Dalanated Insulin
CAS No.	9004-12-0
Molecular Formula	C254H377N65O75S6
Molecular Weight	~5807.9 g/mol
Synonyms	Des-Alanine Insulin; Insulin (Human), Des-Ala; Desalanine Insulin; Insulin, des-Ala-; [Des-Ala]Insulin; Insulin derivative (des-Ala); 9004-12-0; Insulin, dalanated
EINECS	Contact for details

Quality Control

Our Dalanated Insulin is manufactured under strict quality management systems. Each batch is subjected to a comprehensive suite of analytical tests, including HPLC for purity, peptide mapping for sequence confirmation, and mass spectrometry for identity verification. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes to ensure compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); ensure containers are sealed under anhydrous conditions or with desiccant. For short-term use, store at 2-8°C. Allow the product to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Proteins (HPLC)	≤ 5.0%
Water Content (KF)	≤ 5.0%
Peptide Content (UV)	≥ 80.0%
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.