Description

A-Melanocyte Stimulating Hormone Synthetic is a synthetic peptide analog of the endogenous α-melanocyte-stimulating hormone (α-MSH). This compound is of significant interest for its role in melanogenesis and its broader physiological functions, including anti-inflammatory and immunomodulatory activity. It serves as a critical research biochemical and a potential precursor in pharmaceutical development for skin pigmentation disorders and metabolic research.

Application

• Biomedical Research: Used as a standard or tool compound in studies investigating melanocortin receptor (MC1R) signaling pathways, skin biology, and pigmentation mechanisms.
• Pharmaceutical Development: Acts as a key intermediate or reference standard in the R&D of novel therapeutics targeting vitiligo, erythropoietic protoporphyria, or inflammatory conditions.
• Cosmeceutical Research: Employed in vitro and in vivo studies to evaluate compounds that may modulate skin tanning or pigmentation for potential cosmetic applications.
• Metabolic Studies: Utilized in research exploring the role of melanocortins in appetite regulation, energy homeostasis, and sexual function.
• Cell Culture & Assays: Serves as a ligand in receptor binding assays, functional cell-based tests, and signal transduction studies.
• Quality Control: Functions as a high-purity reference material for the calibration and validation of analytical methods in peptide manufacturing.

Basic Information

Product Name	A-Melanocyte Stimulating Hormone Synthetic
CAS No.	9002-79-3
Molecular Formula	C77H109N21O19S
Molecular Weight	1664.9 g/mol
Synonyms	α-MSH; α-Melanocyte Stimulating Hormone; α-Melanotropin; Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2; Melanotropin alpha; Intermedin; Afamelanotide (API related); [Nle4, D-Phe7]-α-MSH (analog related); Melanocortin (1-13) peptide amide
EINECS	Contact for details

Quality Control

Our A-Melanocyte Stimulating Hormone Synthetic is manufactured under strict quality systems. Each batch is characterized and tested to ensure identity, purity, and biological activity, meeting high standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing HPLC purity, peptide content, amino acid analysis, and mass spectrometry (MS) data is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Biological Activity	Assayed (In vitro melanocyte assay or receptor binding)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.