Description

L-Saccharopine is a key intermediate in the lysine biosynthesis pathway, specifically in the saccharopine pathway found in higher eukaryotes and some fungi. This compound is of significant interest in biochemical research and pharmaceutical development due to its role in amino acid metabolism. It is primarily utilized by researchers in life sciences, pharmaceutical R&D, and biotechnology sectors studying metabolic disorders, enzyme kinetics, and pathway engineering.

Application

• Biochemical Research: Critical substrate for studying the enzymes lysine-ketoglutarate reductase (LKR) and saccharopine dehydrogenase (SDH) in the lysine degradation pathway.
• Metabolic Disorder Studies: Used in research models for hyperlysinemia, a rare inborn error of metabolism, to understand disease mechanisms and potential therapeutic interventions.
• Enzyme Assay Development: Serves as a standard or reagent in developing and validating assays for LKR and SDH enzyme activity.
• Pharmaceutical Intermediates: Potential building block or reference compound in the synthesis of more complex molecules targeting metabolic pathways.
• Nutritional Science Research: Investigated for its role and implications in amino acid metabolism and bioavailability.
• Diagnostic Kit Manufacturing: May be used as a component in diagnostic kits for measuring relevant enzyme activities in clinical or research settings.

Basic Information

Product Name	L-Saccharopine
CAS No.	997-68-2
Molecular Formula	C11H20N2O6
Molecular Weight	276.29 g/mol
Synonyms	L-Saccharopine; Saccharopine; (2S)-2-[(5S)-5-Amino-5-carboxypentyl]amino-pentanedioic acid; N6-(L-1,3-Dicarboxypropyl)-L-lysine; N6-(1,3-Dicarboxypropyl)-L-lysine; L-Lysine, N6-(1,3-dicarboxypropyl)-, (S)-; Lysine, N6-(L-1,3-dicarboxypropyl)-, L-
EINECS	213-637-4

Quality Control

Our L-Saccharopine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, physical characteristics, and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]D20: Contact for details
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.