Description

Potassium Hydrogen 2-Oxoglutarate is the potassium salt of 2-oxoglutaric acid, a key intermediate in the Krebs cycle. This high-purity biochemical is essential for research and manufacturing processes requiring a stable, bioavailable source of α-ketoglutarate. It is primarily utilized by the pharmaceutical, nutraceutical, and life science research industries for applications in cell culture media, metabolic studies, and as a precursor in synthesis.

Application

• Biochemical Research & Cell Culture: Serves as a critical component in cell culture media and buffers, supporting cellular metabolism and growth studies.
• Pharmaceutical Intermediates: Used as a building block in the synthesis of more complex active pharmaceutical ingredients (APIs) and diagnostic agents.
• Nutraceutical Formulations: Incorporated into dietary supplements targeting energy metabolism, athletic performance, and anti-aging, often as a source of α-ketoglutarate (AKG).
• Enzymology & Diagnostic Kits: Acts as a specific substrate for enzymes like glutamate dehydrogenase, used in clinical diagnostic assays and enzyme activity studies.
• Microbiology & Fermentation: Employed in microbial culture media to support the growth of specific microorganisms in industrial fermentation processes.

Basic Information

Product Name	Potassium Hydrogen 2-Oxoglutarate
CAS No.	997-43-3
Molecular Formula	C5H5KO5
Molecular Weight	184.19 g/mol
Synonyms	Potassium 2-oxoglutarate; Potassium α-ketoglutarate; Potassium oxoglutarate; 2-Oxopentanedioic acid potassium salt; α-Ketoglutaric acid potassium salt; AKG potassium salt; Oxoglutaric acid potassium salt
EINECS	213-635-4

Quality Control

Our Potassium Hydrogen 2-Oxoglutarate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, heavy metals, and loss on drying. Specifications can be tailored to meet research-grade, pharmaceutical intermediate, or nutraceutical-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
pH (5% solution)	3.0 - 4.5
Loss on Drying	≤ 2.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.