Description

Cyclo(Leu-Leu) CAS NO 952-45-4 is a cyclic dipeptide, also known as a diketopiperazine (DKP), formed from two leucine amino acids. This compound serves as a crucial building block and intermediate in advanced pharmaceutical research and peptide synthesis. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of more complex peptide-based drugs and prodrugs.
• Biochemical Research: Used as a model compound in studies of peptide conformation, stability, and cyclization mechanisms.
• Protease Inhibitor Scaffold: Serves as a core structure in the design and synthesis of enzyme inhibitors.
• Cosmetic Peptide Precursor: Acts as a starting material for synthesizing bioactive peptides used in skincare formulations.
• Chemical Biology Tool: Employed in exploring protein-protein interactions and cell signaling pathways.
• Fine Chemical Synthesis: A versatile chiral building block for asymmetric synthesis in advanced organic chemistry.

Basic Information

Product Name	Cyclo(Leu-Leu)
CAS No.	952-45-4
Molecular Formula	C12H22N2O2
Molecular Weight	226.32 g/mol
Synonyms	Cyclo(L-leucyl-L-leucyl); 3,6-Diisopropyl-2,5-piperazinedione; L-Leucyl-L-leucine anhydride; Cyclo(L-Leu-L-Leu); Diketopiperazine of L-Leucine; LL-Cyclo(leucylleucine); (3S,6S)-3,6-Diisopropylpiperazine-2,5-dione; Leu-Leu DKP
EINECS	213-451-7

Quality Control

Our Cyclo(Leu-Leu) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.