Description

L-Homophe-Oh CAS NO 943-73-7 is a specialized chiral amino acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a unique phenylalanine-like side chain with modified stereochemistry, enabling the creation of novel compounds with targeted biological activity. This high-purity intermediate is essential for research and production in the pharmaceutical and biotechnology sectors, particularly for developing peptide-based therapeutics and enzyme inhibitors.

Application

• Pharmaceutical Intermediates: Key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially in metabolic and neurological research.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide chemistry to incorporate non-natural amino acid residues, modifying peptide stability and receptor binding.
• Biochemical Research: Serves as a precursor or standard in enzymatic studies and metabolic pathway analysis.
• Asymmetric Catalysis: Employed as a ligand or building block for chiral catalysts and auxiliaries in stereoselective synthesis.
• Proteomics & Diagnostics: Can be used in the development of specialized probes, labels, or affinity tags for protein analysis.

Basic Information

Product Name	L-Homophe-Oh
CAS No.	943-73-7
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	(S)-2-Amino-4-phenylbutanoic acid; L-2-Amino-4-phenylbutyric acid; L-Homophenylalanine; L-4-Phenyl-2-aminobutanoic acid; Hph; L-HPA; (S)-HomoPhe; Fmoc-Hph-OH (protected form)
EINECS	213-403-8

Quality Control

Our L-Homophe-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC chromatograms and spectroscopic data. The product meets stringent specifications suitable for pharmaceutical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Optical Rotation [α]D20	-20.0° to -24.0° (c=1 in 1N HCl)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤10 ppm
Chiral Purity (HPLC)	≥99.0% (L-isomer)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.