Description

4-Amino-2-(Trifluoromethyl)Pyrimidine-5-Carbonitrile is a high-value, multi-functional pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its unique trifluoromethyl-substituted pyrimidine core offers significant advantages in modulating the physicochemical properties of target molecules, making it indispensable for research and development. This compound is primarily sought after by pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of antiviral, anticancer, and kinase inhibitor drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances bioactivity and environmental stability.
• Material Science Precursor: Employed in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry and organic synthesis for structure-activity relationship (SAR) studies.
• Fluorine Chemistry Building Block: Provides a source of the trifluoromethyl group for introducing fluorine atoms into complex molecules to improve metabolic stability and lipophilicity.

Basic Information

Product Name	4-Amino-2-(Trifluoromethyl)Pyrimidine-5-Carbonitrile
CAS No.	943-25-9
Molecular Formula	C6H3F3N4
Molecular Weight	188.11 g/mol
Synonyms	2-(Trifluoromethyl)-4-aminopyrimidine-5-carbonitrile; 5-Cyano-2-(trifluoromethyl)pyrimidin-4-amine; 4-Amino-2-trifluoromethyl-5-pyrimidinecarbonitrile; 4-Amino-2-(trifluoromethyl)-5-pyrimidinecarbonitrile; 4-Amino-2-(trifluoromethyl)pyrimidine-5-carbonitrile; 2-Trifluoromethyl-4-amino-5-cyanopyrimidine
EINECS	Contact for details

Quality Control

Our 4-Amino-2-(Trifluoromethyl)Pyrimidine-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP standards where applicable, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in original packaging away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.