Description

H-Ala-Ala-Ala-Ala-OH is a high-purity, synthetic tetrapeptide composed of four consecutive L-alanine amino acid residues with a free C-terminal carboxylic acid. This well-defined oligopeptide is a critical building block and model compound in biochemical and pharmaceutical research. It serves as an essential tool for researchers and manufacturers in the fields of peptide synthesis, enzymology, and drug discovery.

Application

• Peptide Synthesis & Research: Used as a standard reference compound, a model substrate for proteolytic enzyme studies, and a building block for constructing longer, more complex peptide sequences.
• Biochemical Research: Serves as a substrate for investigating the specificity and kinetics of enzymes like proteases, peptidases, and aminopeptidases.
• Pharmaceutical Development: Employed in the research and development of peptide-based therapeutics, vaccines, and diagnostic agents.
• Academic & Industrial R&D: A fundamental reagent in laboratories for studying peptide structure, folding, stability, and aggregation properties.
• Quality Control Standard: Acts as a certified reference material (CRM) or analytical standard for calibrating equipment and validating methods in QC/QA laboratories.

Basic Information

Product Name	H-Ala-Ala-Ala-Ala-OH
CAS No.	926-79-4
Molecular Formula	C12H21N4O5
Molecular Weight	301.32 g/mol
Synonyms	L-Alanyl-L-alanyl-L-alanyl-L-alanine; Tetralanine; Ala-Ala-Ala-Ala; AAAA; Poly-L-alanine (tetramer); H-Ala-Ala-Ala-Ala-OH; N-(L-Alanyl)-L-alanyl-L-alanyl-L-alanine; (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]propanoyl]amino]propanoyl]amino]propanoic acid
EINECS	Contact for details

Quality Control

Our H-Ala-Ala-Ala-Ala-OH is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric purity, and identity confirmation via mass spectrometry (MS) and infrared spectroscopy (IR). Certificates of Analysis (COA) with detailed specifications are provided to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be kept under desiccant or inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.