Description

D-Alanyl-D-Alanine CAS NO 923-16-0 is a high-purity dipeptide consisting of two D-alanine residues. This compound serves as a critical biochemical building block and substrate in advanced research and pharmaceutical synthesis. It is essential for researchers and manufacturers in the fields of antibiotic development, enzymology, and peptide chemistry. Our product is supplied to meet the stringent quality requirements of these demanding applications.

Application

• Biochemical Research: Used as a specific substrate for studying bacterial cell wall biosynthesis enzymes, such as D-alanyl-D-alanine carboxypeptidases and transpeptidases.
• Antibiotic Development: Acts as a key intermediate and target molecule in the research and synthesis of glycopeptide antibiotics (e.g., vancomycin) and other antimicrobial agents that inhibit peptidoglycan formation.
• Enzyme Inhibition Studies: Employed in assays to screen for and characterize novel inhibitors of bacterial enzymes involved in peptidoglycan assembly, supporting drug discovery efforts.
• Peptide Synthesis: Serves as a specialized building block for the chemical synthesis of complex peptides and peptidomimetics with specific D-amino acid configurations.
• Microbiology & Diagnostics: Utilized in microbial growth media and diagnostic tests related to bacterial resistance mechanisms, particularly vancomycin resistance (VanA, VanB phenotypes).
• Reference Standard: Provides a high-purity analytical standard for quality control and method development in pharmaceutical and research laboratories.

Basic Information

Product Name	D-Alanyl-D-Alanine
CAS No.	923-16-0
Molecular Formula	C6H12N2O4
Molecular Weight	176.17 g/mol
Synonyms	D-Ala-D-Ala; (R)-2-((R)-2-Aminopropanamido)propanoic acid; D-2-Aminopropionyl-D-alanine; D-Alanyl-D-alanine; H-D-Ala-D-Ala-OH; DADALA; DD-Dipeptide; NSC 334365; Alanylalanine, D- isomer
EINECS	213-090-4

Quality Control

Our D-Alanyl-D-Alanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% D,D-isomer
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.