Description

(6R,2S)-Diaminopimelic Acid CAS NO 922-54-3 is a high-purity, stereochemically defined isomer of diaminopimelic acid (DAP), a key intermediate in the biosynthesis of lysine and a critical component of bacterial cell wall peptidoglycan. This specific enantiomer is essential for advanced biochemical research and the development of targeted antimicrobial agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on microbiology, enzymology, and novel antibiotic discovery.

Application

• Biochemical Research: Critical substrate and reference standard for studying the lysine biosynthesis pathway and bacterial cell wall assembly.
• Enzyme Inhibition Studies: Used to investigate and characterize enzymes like diaminopimelate decarboxylase (DAPDC) and other targets within microbial metabolism.
• Antimicrobial Development: Serves as a core structural component or inhibitor template in the design of novel antibiotics targeting bacterial peptidoglycan synthesis.
• Microbiology & Cell Culture: Employed in defined media formulations for the growth and study of bacterial mutants, particularly those auxotrophic for lysine or DAP.
• Pharmaceutical Intermediates: Acts as a chiral building block for the synthesis of more complex pharmaceutical compounds and diagnostic agents.
• Diagnostic Reagent Manufacturing: Used in the production of reagents for bacterial identification and metabolic pathway analysis.

Basic Information

Product Name	(6R,2S)-Diaminopimelic Acid
CAS No.	922-54-3
Molecular Formula	C7H14N2O4
Molecular Weight	190.20 g/mol
Synonyms	(2S,6R)-2,6-Diaminopimelic Acid; (2S,6R)-DAP; DAP; meso-Diaminopimelic Acid; (R,S)-Diaminopimelic Acid; 2,6-Diaminoheptanedioic Acid; Bacterial Cell Wall Component; Lysine Biosynthesis Intermediate
EINECS	Contact for details

Quality Control

Our (6R,2S)-Diaminopimelic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing specific results for assay, enantiomeric excess, and related substances are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% (6R,2S)-isomer
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.